How Long Does Modafinil Last?

How Long Does Modafinil Stay In Your System

Modafinil has shaken the pharmaceutical market for all good reasons. Belonging to the class of nootropic medicines, the medicine has set a bar in the market of wakefulness promoter agents. It is useful in removal of excessive daytime sleepiness or hypersomnia caused by sleep issues such as narcolepsy, obstructive sleep apnea, restless leg syndrome, insomnia etc. Modafinil is also used as a cognitive enhancer. It has shown positive effects in betterment of cognitive health and memory processing and recalling.

How does it work?

Modafinil majorly works on the neurotransmitters. These are also involved in maintaining sleep-wake up cycle. The medicine helps in retaining these chemicals within the brain for longer by preventing their re-uptake process. The longer these neurotransmitters stay in the brain, a person stays awake longer. Also, they have positive effects on the cognitive functions and concentration.

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How does it stay in your body?

Modafinil, taken once in a day, is capable of giving you results for 14 to 16 hours. It is because the half-life of the medicines varies from 12 to 14 hours. The time span changes because the half-life depends on several factors such as genetic structure of a consumer, kidney and liver functioning etc.

How long does Modafinil stay in your hair, blood, and urine?

As mentioned before, the half-life of Modafinil revolves around many factors. In most of the cases, Modafinil is excreted as one of the forms of its metabolites – modafinil acid or modafinil sulfone. The medication and its metabolites can be present in the urine for up to 30 hours post consumption. They can be found and analyzed in the plasma, urine, and serum. Liquid chromatography or gas chromatography is used to detect the presence of the medicine and its metabolites in vehicle accident cases and post-mortem evaluation.

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